Influence of Cell Quality on Inflammatory Biomarkers in COPD Sputum Supernatant
نویسندگان
چکیده
منابع مشابه
Sputum cell count: biomarkers in the differentiation of asthma, COPD and asthma–COPD overlap
INTRODUCTION Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. Nevertheless, the clinical application of sputum cell counts in patients with asthma-COPD overlap (ACO) remains elusive. The aim of this study was to investigate sputum cell counts in patients wit...
متن کاملBlood and sputum biomarkers in COPD and asthma: a review.
Chronic obstructive pulmonary disease (COPD) and asthma are lung inflammatory diseases that represent major public health problems. The primary, and often unique, method to evaluate lung function is spirometry, which reflects disease severity rather than disease activity. Moreover, its measurements strictly depend on patient's compliance, physician's expertise and data interpretation. The limit...
متن کاملInflammatory biomarkers in asthma-COPD overlap syndrome
BACKGROUND The clinical phenotypes and underlying mechanisms of asthma-COPD overlap syndrome (ACOS) remain elusive. This study aimed to investigate a comparison of COPD patients with and without ACOS, focusing on inflammatory biomarkers, in an outpatient COPD cohort. METHODS We conducted a cross-sectional study analyzing prospectively collected data from the Ishinomaki COPD Network registry. ...
متن کاملLeukotriene B4 in exhaled breath condensate and sputum supernatant in patients with COPD and asthma.
STUDY OBJECTIVES Some patients with COPD present with significant reversibility of airflow limitation after receiving bronchodilation therapy. Leukotriene B(4) (LTB(4)) has been implicated in the pathophysiology of both COPD and asthma. We tested the hypothesis that COPD patients with airflow reversibility and asthmatic patients who smoke might have similar levels of LTB(4) in exhaled breath co...
متن کاملCharacterization of sputum biomarkers for asthma–COPD overlap syndrome
Asthma-COPD overlap syndrome (ACOS) is a commonly encountered chronic airway disease. However, ACOS is still a consensus-based clinical phenotype and the underlying inflammatory mechanisms are inadequately characterized. To clarify the inflammatory mediatypical for ACOS, five biomarkers, namely interleukin (IL)-13, myeloperoxidase (MPO), neutrophil gelatinase-associated lipocalin (NGAL), chitin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2021
ISSN: 1178-2005
DOI: 10.2147/copd.s284938